MANUEL
PORTERO OTIN
CU
Centro de Investigación Biomédica en Red sobre Enfermedades Raras
Madrid, EspañaPublications en collaboration avec des chercheurs de Centro de Investigación Biomédica en Red sobre Enfermedades Raras (13)
2023
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Sphingolipid desaturase DEGS1 is essential for mitochondria-associated membrane integrity
The Journal of clinical investigation, Vol. 133, Núm. 10
2022
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Cardiac fibroblasts display endurance to ischemia, high ROS control and elevated respiration regulated by the JAK2/STAT pathway
FEBS Journal, Vol. 289, Núm. 9, pp. 2540-2561
2021
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Lipid alterations in human frontal cortex in ALS-FTLD-TDP43 proteinopathy spectrum are partly related to peroxisome impairment
Neuropathology and Applied Neurobiology, Vol. 47, Núm. 4, pp. 544-563
2018
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Aberrant regulation of the GSK-3β/NRF2 axis unveils a novel therapy for adrenoleukodystrophy
EMBO Molecular Medicine, Vol. 10, Núm. 8
2017
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Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance
Aging Cell, Vol. 16, Núm. 6, pp. 1404-1413
2016
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Targeted activation of CREB in reactive astrocytes is neuroprotective in focal acute cortical injury
GLIA, Vol. 64, Núm. 5, pp. 853-874
2015
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Deregulation of purine metabolism in Alzheimer's disease
Neurobiology of Aging, Vol. 36, Núm. 1, pp. 68-80
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Neuroinflammatory signals in alzheimer disease and APP/PS1 transgenic mice: Correlations with plaques, tangles, and oligomeric species
Journal of Neuropathology and Experimental Neurology, Vol. 74, Núm. 4, pp. 319-344
2012
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Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: A paradigm for multifactorial neurodegenerative diseases?
Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1822, Núm. 9, pp. 1475-1488
2011
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Antioxidants halt axonal degeneration in a mouse model of X-adrenoleukodystrophy
Annals of Neurology, Vol. 70, Núm. 1, pp. 84-92
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Oxidative damage compromises energy metabolism in the axonal degeneration mouse model of X-adrenoleukodystrophy
Antioxidants and Redox Signaling, Vol. 15, Núm. 8, pp. 2095-2107
2010
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Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy
Human Molecular Genetics, Vol. 19, Núm. 10, pp. 2005-2014
2008
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Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy
Human Molecular Genetics, Vol. 17, Núm. 12, pp. 1762-1773