- Medicina Experimental
Departament
![Foto de Aurora](/img/nophoto.png)
Aurora
Pujol
Publicacións nas que colabora con Aurora Pujol (20)
2022
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Activating cannabinoid receptor 2 preserves axonal health through GSK-3β/NRF2 axis in adrenoleukodystrophy
Acta Neuropathologica, Vol. 144, Núm. 2, pp. 241-258
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Modulation of mitochondrial and inflammatory homeostasis through RIP140 is neuroprotective in an adrenoleukodystrophy mouse model
Neuropathology and Applied Neurobiology, Vol. 48, Núm. 1
2021
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Lipid alterations in human frontal cortex in ALS-FTLD-TDP43 proteinopathy spectrum are partly related to peroxisome impairment
Neuropathology and Applied Neurobiology, Vol. 47, Núm. 4, pp. 544-563
2019
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Biomarker Identification, Safety, and Efficacy of High-Dose Antioxidants for Adrenomyeloneuropathy: a Phase II Pilot Study
Neurotherapeutics, Vol. 16, Núm. 4, pp. 1167-1182
2018
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Aberrant regulation of the GSK-3β/NRF2 axis unveils a novel therapy for adrenoleukodystrophy
EMBO Molecular Medicine, Vol. 10, Núm. 8
2017
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Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance
Aging Cell, Vol. 16, Núm. 6, pp. 1404-1413
2016
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Targeted activation of CREB in reactive astrocytes is neuroprotective in focal acute cortical injury
GLIA, Vol. 64, Núm. 5, pp. 853-874
2015
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Activation of sirtuin 1 as therapy for the peroxisomal disease adrenoleukodystrophy
Cell Death and Differentiation, Vol. 22, Núm. 11, pp. 1742-1753
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Altered glycolipid and glycerophospholipid signaling drive inflammatory cascades in adrenomyeloneuropathy
Human Molecular Genetics, Vol. 24, Núm. 24, pp. 6861-6876
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Deregulation of purine metabolism in Alzheimer's disease
Neurobiology of Aging, Vol. 36, Núm. 1, pp. 68-80
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Neuroinflammatory signals in alzheimer disease and APP/PS1 transgenic mice: Correlations with plaques, tangles, and oligomeric species
Journal of Neuropathology and Experimental Neurology, Vol. 74, Núm. 4, pp. 319-344
2014
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Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity
Human Molecular Genetics, Vol. 23, Núm. 14, pp. 3716-3732
2013
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Impaired mitochondrial oxidative phosphorylation in the peroxisomal disease X-linked adrenoleukodystrophy
Human Molecular Genetics, Vol. 22, Núm. 16, pp. 3296-3305
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Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy
Brain, Vol. 136, Núm. 8, pp. 2432-2443
2012
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Amyloid generation and dysfunctional immunoproteasome activation with disease progression in animal model of familial Alzheimer's disease
Brain Pathology, Vol. 22, Núm. 5, pp. 636-653
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Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: A paradigm for multifactorial neurodegenerative diseases?
Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1822, Núm. 9, pp. 1475-1488
2011
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Antioxidants halt axonal degeneration in a mouse model of X-adrenoleukodystrophy
Annals of Neurology, Vol. 70, Núm. 1, pp. 84-92
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Oxidative damage compromises energy metabolism in the axonal degeneration mouse model of X-adrenoleukodystrophy
Antioxidants and Redox Signaling, Vol. 15, Núm. 8, pp. 2095-2107
2010
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Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy
Human Molecular Genetics, Vol. 19, Núm. 10, pp. 2005-2014
2008
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Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy
Human Molecular Genetics, Vol. 17, Núm. 12, pp. 1762-1773