- Institut de Recerca Biomèdica de Lleida (IRB-Lleida)
Institut d'investigació
LIDIA PIEDRAFITA LLORENS-rekin lankidetzan egindako argitalpenak (25)
2023
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Persistent NRG1 Type III Overexpression in Spinal Motor Neurons Has No Therapeutic Effect on ALS-Related Pathology in SOD1G93A Mice
Neurotherapeutics, Vol. 20, Núm. 6, pp. 1820-1834
2022
2021
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Beneficial effects of dietary supplementation with green tea catechins and cocoa flavanols on aging-related regressive changes in the mouse neuromuscular system
Aging, Vol. 13, Núm. 14, pp. 18051-18093
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Microglial recruitment and mechanisms involved in the disruption of afferent synaptic terminals on spinal cord motor neurons after acute peripheral nerve injury
GLIA, Vol. 69, Núm. 5, pp. 1216-1240
2020
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Motoneuron deafferentation and gliosis occur in association with neuromuscular regressive changes during ageing in mice
Journal of Cachexia, Sarcopenia and Muscle, Vol. 11, Núm. 6, pp. 1628-1660
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The Y172 Monoclonal Antibody Against p-c-Jun (Ser63) Is a Marker of the Postsynaptic Compartment of C-Type Cholinergic Afferent Synapses on Motoneurons
Frontiers in Cellular Neuroscience, Vol. 13
2019
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Localization and dynamic changes of neuregulin-1 at C-type synaptic boutons in association with motor neuron injury and repair
FASEB Journal, Vol. 33, Núm. 7, pp. 7833-7851
2018
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Accumulation of poly(A) RNA in nuclear granules enriched in Sam68 in motor neurons from the SMNΔ7 mouse model of SMA
Scientific Reports, Vol. 8, Núm. 1
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Glial activation and central synapse loss, but not motoneuron degeneration, are prevented by the sigma-1 receptor agonist pre-084 in the SMN2B/ mouse model of spinal muscular atrophy
Journal of Neuropathology and Experimental Neurology, Vol. 77, Núm. 7, pp. 577-597
2017
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Cellular bases of the RNA metabolism dysfunction in motor neurons of a murine model of spinal muscular atrophy: Role of Cajal bodies and the nucleolus
Neurobiology of Disease, Vol. 108, pp. 83-99
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Neuregulin 1-ErbB module in C-bouton synapses on somatic motor neurons: Molecular compartmentation and response to peripheral nerve injury
Scientific Reports, Vol. 7
2016
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Chronic Treatment with the AMPK Agonist AICAR Prevents Skeletal Muscle Pathology but Fails to Improve Clinical Outcome in a Mouse Model of Severe Spinal Muscular Atrophy
Neurotherapeutics, Vol. 13, Núm. 1, pp. 198-216
2014
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Accumulation of misfolded SOD1 in dorsal root ganglion degenerating proprioceptive sensory neurons of transgenic mice with amyotrophic lateral sclerosis
BioMed Research International, Vol. 2014
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Neuregulin-1 is concentrated in the postsynaptic subsurface cistern of C-bouton inputs to α-motoneurons and altered during motoneuron diseases
FASEB Journal, Vol. 28, Núm. 8, pp. 3618-3632
2013
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Chronic treatment with lithium does not improve neuromuscular phenotype in a mouse model of severe spinal muscular atrophy
Neuroscience, Vol. 250, pp. 417-433
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Immunodetection of disease-associated conformers of mutant Cu/Zn superoxide dismutase 1 selectively expressed in degenerating neurons in amyotrophic lateral sclerosis
Journal of Neuropathology and Experimental Neurology, Vol. 72, Núm. 7, pp. 646-661
2011
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Defective neuromuscular junction organization and postnatal myogenesis in mice with severe spinal muscular atrophy
Journal of Neuropathology and Experimental Neurology, Vol. 70, Núm. 6, pp. 444-461
2010
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Increased intramuscular nerve branching and inhibition of programmed cell death of chick embryo motoneurons by immunoglobulins from patients with motoneuron disease
Journal of Neuroimmunology, Vol. 229, Núm. 1-2, pp. 157-168
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Lithium prevents excitotoxic cell death of motoneurons in organotypic slice cultures of spinal cord
Neuroscience, Vol. 165, Núm. 4, pp. 1353-1369
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Neurotoxic species of misfolded SOD1G93A recognized by antibodies against the P2X4 subunit of the ATP receptor accumulate in damaged neurons of transgenic animal models of amyotrophic lateral sclerosis
Journal of Neuropathology and Experimental Neurology, Vol. 69, Núm. 2, pp. 176-187