MANUEL
PORTERO OTIN
CU
Institut d'Investigació Biomédica de Bellvitge
Barcelona, EspañaPublicacións en colaboración con investigadores/as de Institut d'Investigació Biomédica de Bellvitge (18)
2023
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Ether Lipid-Mediated Antioxidant Defense in Alzheimer’s Disease
Antioxidants, Vol. 12, Núm. 2
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Lipid Adaptations against Oxidative Challenge in the Healthy Adult Human Brain
Antioxidants, Vol. 12, Núm. 1
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Sphingolipid desaturase DEGS1 is essential for mitochondria-associated membrane integrity
The Journal of clinical investigation, Vol. 133, Núm. 10
2022
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Activating cannabinoid receptor 2 preserves axonal health through GSK-3β/NRF2 axis in adrenoleukodystrophy
Acta Neuropathologica, Vol. 144, Núm. 2, pp. 241-258
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Modulation of mitochondrial and inflammatory homeostasis through RIP140 is neuroprotective in an adrenoleukodystrophy mouse model
Neuropathology and Applied Neurobiology, Vol. 48, Núm. 1
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Selective brain regional changes in lipid profile with human aging
GeroScience, Vol. 44, Núm. 2, pp. 763-783
2021
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Lipid alterations in human frontal cortex in ALS-FTLD-TDP43 proteinopathy spectrum are partly related to peroxisome impairment
Neuropathology and Applied Neurobiology, Vol. 47, Núm. 4, pp. 544-563
2019
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Altered dynein axonemal assembly factor 1 expression in C-boutons in bulbar and spinal cord motor-neurons in sporadic amyotrophic lateral sclerosis
Journal of Neuropathology and Experimental Neurology, Vol. 78, Núm. 5, pp. 416-425
2018
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Aberrant regulation of the GSK-3β/NRF2 axis unveils a novel therapy for adrenoleukodystrophy
EMBO Molecular Medicine, Vol. 10, Núm. 8
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High-carotenoid maize: development of plant biotechnology prototypes for human and animal health and nutrition
Phytochemistry Reviews, Vol. 17, Núm. 2, pp. 195-209
2017
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Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance
Aging Cell, Vol. 16, Núm. 6, pp. 1404-1413
2015
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Activation of sirtuin 1 as therapy for the peroxisomal disease adrenoleukodystrophy
Cell Death and Differentiation, Vol. 22, Núm. 11, pp. 1742-1753
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Deregulation of purine metabolism in Alzheimer's disease
Neurobiology of Aging, Vol. 36, Núm. 1, pp. 68-80
2013
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Dietary intake of green tea polyphenols regulates insulin sensitivity with an increase in AMP-activated protein kinase α content and changes in mitochondrial respiratory complexes
Molecular Nutrition and Food Research, Vol. 57, Núm. 3, pp. 459-470
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Impaired mitochondrial oxidative phosphorylation in the peroxisomal disease X-linked adrenoleukodystrophy
Human Molecular Genetics, Vol. 22, Núm. 16, pp. 3296-3305
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Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy
Brain, Vol. 136, Núm. 8, pp. 2432-2443
2012
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Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: A paradigm for multifactorial neurodegenerative diseases?
Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1822, Núm. 9, pp. 1475-1488
2011
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Antioxidants halt axonal degeneration in a mouse model of X-adrenoleukodystrophy
Annals of Neurology, Vol. 70, Núm. 1, pp. 84-92